WV-INBRE
2006 Summer Research Symposium

POSTER PRESENTATIONS

Sixty two poster presentations were made at the 2006 Summer Research Symposium. Participants included interns from the Summer Research Program and faculty and students from the predominantly undergraduate colleges and universities whose research is supported by the WV-INBRE and summer interns supported by the Mary Babb Randolph Cancer Center Summer Research Program.

Presenters are underlined.

(See also the Photos of Poster Presentations)

Posters Presented by the WV-INBRE Participants

Variations in the Genetic Coding Sequence of AGP and its Effect on the Binding Rate of Docetaxel in the Blood Plasma of Prostate Cancer Patients,
Kristina Bacon, Jing Jie Yu, Terry McManhus , Xiaobing Liang , Qi He ,
William Petros

Early Expression Profiles of Chemokines During Chlamydia Infection,
Tesfaye Belay, Anthony Woart, E.L. Barr, S. Kimbro, F.O. Eko, J.U. Igietseme, G. A. Ananaba [View photo]

Cloning of Collagen-Like Proteins BclD and BclE of Bacillus anthracis,
Stephanie Boblett, Christopher Garton, Clayton Caswell, Ewa Lukomska, Slawomir Lukomski [View photo]

Effects of Reovirus on Peanut Allergies: A Model to Test the Hygiene Hypothesis, Ryan Busch, Ronald Fecek, Cynthia A. Cunningham, and Christopher F. Cuff [View photo]

Alginate Production In Pseudomonas Fluorescens Is Regulated By The MucA Pathway, Danielle H. Carroll, Vonya M. Eisinger, Hongwei D. Yu

Effect of Flavonoids in Regulating Reactive Oxygen Species and Vascular Endothelial Growth Factor Expression in Human Ovarian Cancer Cells,
Yi Charlie Chen, Chang Xia, Bing-Hua Jiang

Immune Response to Polysaccharide Conjugates Following Exposure to an Endocrine Disruptor, 3,4-Dichloropropionanalide (Propanil),
Gina M Cottrill, Keith D Salazar, Rosana Schafer [View photo]

Bioactivity Screening Of EUPHORBIA MACULATA, EUPHORBIA COROLLATA, and EUONYMUS AMERICANUS Extracts, Darrell Crick, Darla Wise, Daniel Puckett, Joshua Deaton, Jennifer Gills

Molecular Dynamics Study of the 4 and 4’ Substituents of Diphenylsulfone in the Presence of Flurbiprofen in the Active Site of Cytochrome P450 2C9, Eric Danhart, Zachary R. Hartman, Peter M. Gannett, Jarrett S. Aguilar

Effects of Antioxidant Supplementation and Repetitive Loading on the Expression of Antioxidant Genes, Megan Docherty, Michael J. Ryan, Ken B. Geronilla, Emidio E. Pistilli, Janna R. Jackson, Sunjay Mannan, Stephen E. Alway

Detection of Single Nucleotide Polymorphisms within Gene LRP8: Relation to Cardiovascular Disease in West Virginia, Lisa Dofka, Amanda Francis, Robert Kreisberg

3, 4 dichloropropionalide (DCPA) Induced Change to the S17 Mouse Stromal Cell Line, Frederick Garland, Kathleen Brundage [View photo]

Characterization of Collagen-Like Proteins of Bacillus anthracis, Chris Garton, Stephanie Boblett, Clay Caswell, Ewa Lukomska, Slawomir Lukomski [View photo]

Alteration of Acetaminophen Metabolism by the Addition of SAMe Detected by HPLC, Thomas F. Guetzloff , Monica A. Valentovic, Nachette Montgomery

Evaluation of Anti-Cortactin PY421 and PS405 Antibodies, Sunam Gurung, Lesly A. Lopez, Scott A. Weed

Expression and Purification of Recombinant Novel Testis-Specific Mt13 Antigen for Contraceptive Vaccine Development, Jessica Hammons, Rajesh Naz, Rajendran Sellamuthu [View photo]

Resveratrol Affects the Response of A7r5 Cells to Mechanical Stretch,
Robert T. Harris, Rahamthulla S. Shaik, Eric R. Blough, Gary L. Wright

Molecular Dynamics Study of Dapsone and Analogs Bound to Cytochrome P450 2C9, Zachary R. Hartman, Eric Danhart, Peter M. Gannett, Jarrett S. Aguilar

Generating an Antennapedia-GFP-AFAP Fusion Protein to Determine the Role of AFAP-110 in Angiogenesis, PA Hartman, BL Venci, M Porta1, BM Fenner, DC Flynn, RD Shurina

Assessing the Correlation of Homocysteine Levels with TCII, RFC, and FOLH Polymorphism, Contessa Hill, Bonnie Freeman, Melinda Huff, Michelle Lindsey, Mark Flood, Jean Chappell, Bowie Kahle, Gary Wright, Todd Green, Paulette Wehner, Mark Studney, Elizabeth Murray

The Formin hDia2 is Expressed in Invadopodia in Human Head and Neck Cancer Cell Lines, Luke G. Huggins, Laura Kelley, Scott A. Weed [View photo]

Energy Analysis of CYP 2C9 In Silico Mutants Using MM_PBSA,
Monica R. Lee, Peter M. Gannett, Jarrett S. Aguilar

Stress-Induced Modulation of Behavioral Responses by Phosphodiesterase-2: Role of Amygdala and Hypothalamus, Katie MacGregor, Anbrin Masood , James O’Donnell [View photo]

Endothelial-Dependent and –Independent Vasodilation in Cerebral Resistance Arteries: Effects of Age and Estrogen Status, Casey McCroskey, Rafael Reyes, Amanda LeBlanc, Judy Muller-Delp

Human Cytochrome P450 2C9 R108I Mutant Created for Future Kinetics Studies Involving Flurbiprofen and Dapsone, Stephanie L. McGary, Jacob R. White, Allan Rettie, Jarrett S. Aguilar, Mary V. O’Connor

The Localization of Neurotrophin Receptors on the Neurons of Airway Ganglia in Ferrets, Joseph M. McLane¹, Thomas Batchelor, Zhong-Xin Wu, Richard D. Dey

Exercise Increases Adiponectin Receptor Expression in the Hypothalamus of Obese Zucker Rats, Sarah Morgan, Amy Sindler, Judy Delp, Jonathan Peterson, Jefferson Frisbee, Randy Bryner, Stan Hileman

Toxicogenomics of the Nephrotoxicant N-(3,5-Dichlorophenyl)- 2-Hydroxysuccinimide (NDHS) in Male Fischer 344 Rats, Jessica Morris, G.O.Rankin, D.K. Anestis [View photo]

2-D QSAR of Cytochrome P450 Substrates and Inhibitors, M.V. O’Connor [View photo]

Effect Of 12(S)-Hete On iNOS AND eNOS Expression In A7r5 Rat Aortic Smooth Muscle Cells, Matthew Palmer, Jennifer Cooke, Jonathan Hess, Todd L. Green [View photo]

In Vitro Effect Of Propanil + 2,4-D On Alloreactive Cytotoxic T Lymphocyte Function, Kendra Policz, Michael Balistreri, Kathleen M. Brundage, James M. Sheil

Internalization of Antennapedia-AFAP-110 and Its Effects on Endothelial Cell Morphology, MJ Porta, PA Hartman, BM Fenner, DC Flynn, RD Shurina

The Synthesis of 8-(Hydroxymethylphenyl)-2’-Deoxyguanosine and Effects upon DNA Conformation, Jonathan Proto, Peter M Gannett, Vorasit Vongsutilers

A Model System For Studying The Effect Of α-Synuclein And Other Aggregating Proteins On The Leakiness Of The Rough Endoplasmic Reticulum, James Reed, Andrew K. Shiemke, William F. Wonderlin

Nitric Oxide-Induced S-Nitrosylation of Bcl-2 Inhibits its Chromium(VI)-Induced Ubiquitination and Proteasomal Degradation, Jill Rotruck, Neelam Azad, Yon Rojanasakul [View photo]

Changes in Cell Surface Proteins Following the Induction of Apoptosis,
Chris Sedlacek, Tracy Serge, Alice Magro, Cynthia Cunningham, Albert Magro

Apoptosis and Steady State mRNA Expression of Cell Surface Proteins,
Tracy Serge, Chris Sedlacek, Alice Magro, Cynthia Cunningham, Albert Magro

Mechanism of Canola Oil to Slow Growth of Breast Cancer Cells,
Masako Shimamoto, Elaine Hardman, Gabriela Ion

Quantum Mechanical/Molecular Mechanical Analysis of CYP 2C9 Substrate Combinations, Brittney Shook, Peter M. Gannett, Jarrett S. Aguilar

A Case for Pro-oxidative Mitochondrial Dysfunction in fALS-linked SOD1 Mutations, Jenny Sisler, Joe Donahue, Michael Gunther [View photo]

Regulation of Histidine Decarboxylase Expression by Cytokines,
Zechary C. Smith, Megan Stephenson, Rob Hayes, Carl Gruetter [View photo]

Correlation of Genotypic Frequencies of Single Nucleotide Polymorphism in HDLBP, LRP1, And APOC3 Genes to Cardiovascular Disease in West Virginia, Cassandra Starkey, Amanda Francis, Robert Kreisberg

Activity Levels in Lean and Genetically Obese Zucker Rats, Melissa Surbaugh, Eunyoung Kim, Ben Dalton, Ryan Morrison, Lawrence Grover, William McCumbee, and Elsa Mangiarua [View photo]

Synthesis, Stability, and Cytotoxicity of the Glutathione-Sulfonium Metabolite of the Anti-Cancer Drug, Busulfan, Rajeev Tajhya, Islam R. Younis, Patrick S. Callery

Detection of Genomic Markers for Cardiovascular Disease; Single Nucleotide Polymorphisms in the LIPA Gene, Chris Taylor, Amanda Francis, Robert Kreisberg

The Effect of a High Fat Diet on Water Consumption in Lean Zucker Rats,
Sabrena Thomas, Jessica Frankel, Ryan Morrison, Kan Huang, William McCumbee, Elsa Mangiarua [View photo]

Evaluation of Aldehyde Dehydrogenase Enzymatic Activity for the Analysis of Stem and Progenitor Cells, Jennifer Thompson, Vincent Sollars [View photo]

Cell Proliferation and Aromatase Activity in Human Prostate Cancer Cell Line BPC-3 in Response to Leptin, Dana Tiberio, Kristina Lopez, Stan Hileman, Linda Vona-Davis

Creation of Membrane-Permeable Fusion Proteins using Antennapedia and the Green Fluorescent Protein in the pGEX Fusion Protein Vector, BL Venci,
PA Hartman, BM Fenner, DC Flynn, RD Shurina

Proteomics Of H-2Kb & H-2Kbm19 Antigenic Peptides, Robert J. Warburton, Alexandria N. Lantz, Heather D. Smith, James M. Sheil [View photo]

Role of MAP Kinase in Growth Hormone Signaling in Rat Hippocampus,
Melanie Ward, Lawrence Grover, Todd Green [View photo]

Human CYP 450 2C9 N204I Created Using Site-Directed Mutagenesis for Future Pharmaceutical Interaction Studies, T.J. Warner, Jacob R. White, Allan Rettie, Jarrett S. Aguilar, Mary V. O’Conner

Determining the Expression of DLC-1 in Human Melanoma Cells,
Renee A. West, Beverly C. Delidow

Detection of Single Nucleotide Polymorphisms in Von Willebrand Factor and Endothelial Lipase for Genomic Markers of Cardiovascular Disease,
De Xiong Zheng, Amanda Francis, Robert Kreisberg

Posters Presented by Mary Babb Randolph Cancer Center Summer Interns

The Protein Phosphatase SHP2 Is Required For Breast Cancer Phenotypes, Alexander Berrebi, Xiangdong Zhou, and Yehenew Agazie

Biomedical Research: Polypeptide Nanocoating for Drug Loading and In Vitro Drug Release, Rajiv Bhattarai, Bingbing Jiang, and Bingyun Li

Real Time In Vivo Remote Sensing of Complete Blood Count Parameters,
Lola Burke, Jame Abraham, Peter Gannet and Peter Perrotta

Synthesis and Characterization of Size-Controlled Gold Nanoparticles for Biological Application, Elizabeth E. Gertz, Huaquing Li, and Nianqiang Wu

Developing a Primary Cerebral Endothelial Cell Culture Method to
Investigate the Blood-Brain Barrier During Hyperglycemia, Michael
Hushion, Reyna VanGilder, Kimbery Houser, and Jason D. Huber

The Interruption of AFAP-110’s PH1 Domain: Preventing the Spread of Cancer, Allison Lastinger, Daniel Flynn, Peter Gannett , and John Jett

Inhibition of Pancreatic Cancer Growth by Catechin and Inositol Hexaphosphate, Brian D. McMillan, Dale R. Rigs, Barbara J. Jackson, Cynthia Cunningham, and David W. McFadden

Inhibition of Breast Cancer Growth by Inositol Hexaphosphate and Peptide Y, Mark A. Robertson, Dale R. Riggs, Barbara J. Jackson, Cynthia Cunningham, and David W. McFadden.